germinal center การใช้

• The germinal centers are supplied by arterioles called " penicilliary radicles ".
• Each germinal center has two parts, a dark zone and a light zone.
• Germinal center B cells may differentiate into memory B cells or plasma cells.
• The development process in the bone marrow occurs in Germinal Centers.
• Therefore, T FR cells are a uniquely inhibitory influence during a germinal center reaction.
• The expression of SERPINA9 is restricted to germinal center B cells and lymphoid malignancies.
• The primary B cell follicle matures in germinal centers.
• Autoreactive B cells can accidentally emerge during somatic hypermutation and migrate into the germinal center light zone.
• The largest methylation difference is between the stages of germinal center B cells and memory B cells.
• It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center.
• "' Burkitt lymphoma "'is a cancer of the lymphatic system, particularly B lymphocytes found in the germinal center.
• SERPINA9 is likely to function in vivo in the germinal center as an efficient inhibitor of trypsin-like proteases.
• Dendritic cells in the germinal center may endocytose such antigenic material and present it to T cells, activating them.
• The number and composition of follicles can change especially when challenged by an antigen, when they develop a germinal center.
• To do so, the few chosen B cells cluster to form so-called germinal centers on the spleen and lymph nodes.
• Multiple myeloma develops in B lymphocytes after they have left the part of the lymph node known as the germinal center.
• Germinal center kinases ( GCKs ), such as TNIK, are characterized by an C-terminal GCK domain that serves a regulatory function.
• Tingible body macrophages ( TBMs )  large phagocytic cells in the germinal centers of secondary lymph nodes  express CD68 protein.
• In agreement with reduced Th2 responses, ICOS-/-mice have reduced germinal center formation and IgG1 and IgE antibody titers in response to immunization.